Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

MK-4827

A potent and selective PARP-1 and PARP-2 inhibitor
Catalog #: 9462
SKU-Size Size Price Qty
9462-5 5 mg
$235.00
9462-25 25 mg
$895.00
More Sizes Get Quote

Product Details

Alternate Name 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide; Niraparib
Appearance Light yellow solid
CAS # 1038915-60-4
Molecular Formula C₁₉H₂₀N₄O
Molecular Weight 320.39
Purity ≥98% by HPLC
Solubility DMSO (>4 mg/ml)
SMILES C1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N
InChi InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1
InChi Key PCHKPVIQAHNQLW-CQSZACIVSA-N
PubChem CID 24958200
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

MK-4827 is a potent and selective PARP-1 and PARP-2 inhibitor with IC₅₀ values of 3.8 nM and 2.1 nM, respectively. It induces synthetic lethality in preclinical tumour models with loss of BRCA and PTEN function.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.