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Product Details
| Alternate Name | [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; Ametycine |
|---|---|
| Appearance | Bluish crystalline solid |
| CAS # | 50-07-7 |
| Molecular Formula | C₁₅H₁₈N₄O₅ |
| Molecular Weight | 334.33 |
| Purity | Potency: ≥970 µg/mg |
| Solubility | DMSO (~15 mg/ml) or H₂O (~0.5 mg/ml) |
| SMILES | CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N |
| InChi | InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1 |
| InChi Key | NWIBSHFKIJFRCO-WUDYKRTCSA-N |
| PubChem CID | 5746 |
| MDL Number | MFCD00078109 |
| Handling | Protect from air and light |
| Storage Conditions | 4°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Mitomycin C is an antitumor antibiotic isolated from Streptomyces sp. Mitomycin is activated by reduction in vivo generating oxygen radicals which produce crosslinks in DNA by alkylaion. This mechanism ultimately inhibits DNA synthesis which has a bacteriostatic effect. Mitomycin C has strong antitumor activity, especially against Ehrlich ascites tumor cells, and strong bactericidal action against gram-positive and gram-negative bacteria.
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Is the product sterile?
The product is available in powder form and is not sterile. However, the solution in appropriate solvent can be sterile filtered.
