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Mitomycin C

An antitumor antibiotic

WARNING: This product can expose you to chemicals including Mitomycin C, which is [are] known to the State of California to cause cancer.  For more information go to www.P65Warnings.ca.gov.
Catalog #: 2713
SKU-Size Size Price Qty
2713-2 2 mg
$65.00
2713-5 5 mg
$95.00
2713-25 25 mg
$345.00
More Sizes Get Quote

Product Details

Alternate Name [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; Ametycine
Appearance Bluish crystalline solid
CAS # 50-07-7
Molecular Formula C₁₅H₁₈N₄O₅
Molecular Weight 334.33
Purity Potency: ≥970 µg/mg
Solubility DMSO (~15 mg/ml) or H₂O (~0.5 mg/ml)
SMILES CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N
InChi InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
InChi Key NWIBSHFKIJFRCO-WUDYKRTCSA-N
PubChem CID 5746
MDL Number MFCD00078109
Handling Protect from air and light
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Mitomycin C is an antitumor antibiotic isolated from Streptomyces sp. Mitomycin is activated by reduction in vivo generating oxygen radicals which produce crosslinks in DNA by alkylaion. This mechanism ultimately inhibits DNA synthesis which has a bacteriostatic effect. Mitomycin C has strong antitumor activity, especially against Ehrlich ascites tumor cells, and strong bactericidal action against gram-positive and gram-negative bacteria.


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Is the product sterile?
The product is available in powder form and is not sterile. However, the solution in appropriate solvent can be sterile filtered.