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Milrinone

A cAMP-specific phosphodiesterase (PDEIII ) inhibitor
Catalog #: 2163
SKU-Size Size Price Qty
2163-5 5 mg
$120.00
2163-25 25 mg
$445.00
More Sizes Get Quote

Product Details

Alternate Name 1,​6-​dihydro-​2-​methyl-​6-​oxo-​[3,​4'-​bipyridine]-​5-​carbonitrile; WIN 47, 203
Appearance Off-white solid
CAS # 78415-72-2
Molecular Formula C₁₂H₉N₃O
Molecular Weight 211.22
Purity ≥98%
Solubility DMSO (10 mg/ml)
SMILES CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2
InChi InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)
InChi Key PZRHRDRVRGEVNW-UHFFFAOYSA-N
PubChem CID 4197
MDL Number MFCD00133539
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A potent, cAMP-specific phosphodiesterase (PDEIII ) inhibitor (IC₅₀ = 0.45 and 1.0 µM for PDEIIIA and PDEIIIB, respectively). It inhibits other PDE isoforms at much higher concentrations. Milrinone has positive inotropic (stimulates cardiac muscle contractions) and vasodilatory effects when administered in vivo.


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