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Miglustat hydrochloride

An inhibitor of α-glucosidase I and II
Catalog #: B3056
SKU-Size Size Price Qty
B3056-1 1 mg
$65.00
B3056-5 5 mg
$260.00
More Sizes Get Quote

Product Details

Alternate Name N-Butyldeoxynojirimycin hydrochloride; NB-DNJ, HCl; (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride; OGT918
Appearance White solid
CAS # 210110-90-0
Molecular Formula C₁₀H₂₂ClNO₄
Molecular Weight 255.74
Purity ≥98%
Solubility ~10 mg/ml in DMSO
SMILES CCCCN1CC(C(C(C1CO)O)O)O.Cl
InChi InChI=1S/C10H21NO4.ClH/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12;/h7-10,12-15H,2-6H2,1H3;1H/t7-,8+,9-,10-;/m1./s1
InChi Key QPAFAUYWVZMWPR-ZSOUGHPYSA-N
PubChem CID 6603107
MDL Number MFCD00269940
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Miglustat is an inhibitor of the N-linked oligosaccharide processing enzymes α-glucosidase I and II. It inhibits rat testicular enzymes ceramide-glucosyltransferase and β-glucosidase 2 with IC50 values of 32 and 81 μM respectively. Miglustat is used for the treatment of type 1 Gaucher’s disease. It is an inhibitor of HIV replication in vitro. It shows activity against SARS-CoV-2 in vitro with EC50 values in the micromolar range.


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