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MHY1485

A potent mTOR activator
Catalog #: 9419
SKU-Size Size Price Qty
9419-5 5 mg
$95.00
9419-25 25 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 4,6-Dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine
Appearance White to off-white solid
CAS # 326914-06-1
Molecular Formula C₁₇H₂₁N₇O₄
Molecular Weight 387.39
Purity ≥98% by HPLC
Solubility DMSO (~ 2 mg/ml)
SMILES C1COCCN1C2=NC(=NC(=N2)NC3=CC=C(C=C3)[N+](=O)[O-])N4CCOCC4
InChi InChI=1S/C17H21N7O4/c25-24(26)14-3-1-13(2-4-14)18-15-19-16(22-5-9-27-10-6-22)21-17(20-15)23-7-11-28-12-8-23/h1-4H,5-12H2,(H,18,19,20,21)
InChi Key MSSXBKQZZINCRI-UHFFFAOYSA-N
PubChem CID 2834965
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

MHY1485 is an mTOR activator that potently inhibits autophagy by suppression of fusion between autophagosomes and lysosomes. Treatment with MHY1485 suppresses the basal autophagic flux, and this inhibitory effect is clearly confirmed in cells under starvation, a strong physiological inducer of autophagy.


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