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ME-0328

A potent PARP-3 inhibitor
Catalog #: 2751
SKU-Size Size Price Qty
2751-5 5 mg
$145.00
2751-25 25 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name 3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide
Appearance White solid
CAS # 1445251-22-8
Molecular Formula C₁₉H₁₉N₃O₂
Molecular Weight 321.37
Purity ≥98% by TLC
Solubility DMSO (~30 mg/ml) or EtOH (~4 mg/ml)
SMILES CC(C1=CC=CC=C1)NC(=O)CCC2=NC(=O)C3=CC=CC=C3N2
InChi InChI=1S/C19H19N3O2/c1-13(14-7-3-2-4-8-14)20-18(23)12-11-17-21-16-10-6-5-9-15(16)19(24)22-17/h2-10,13H,11-12H2,1H3,(H,20,23)(H,21,22,24)/t13-/m0/s1
InChi Key QIHBWVVVRYYYRO-ZDUSSCGKSA-N
PubChem CID 71571526
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

ME-0328 is a potent and selective PARP-3 inhibitor (IC₅₀ = 0.89 µM). ME-0328 inhibits PARP-1, PARP-2 and other ARDTs (ADP ribosyltransferases) at much higher concentrations (IC₅₀ = 6.3, 10.8 and >30 µM, respectively).


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