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MDK-7933

A potent HDAC8 inhibitor
Catalog #: B2119
SKU-Size Size Price Qty
B2119-5 5 mg
$145.00
B2119-25 25 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name (E)-N-hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide; HDAC8-IN-1
Appearance Crystalline solid
CAS # 1417997-93-3
Molecular Formula C₂₂H₁₉NO₃
Molecular Weight 345.4
Purity ≥98% by HPLC
Solubility DMSO
SMILES ONC(/C=C/C1=CC=C(C=C1C2=CC=C(C=C2)C3=CC=CC=C3)OC)=O
InChi nChI=1S/C22H19NO3/c1-26-20-13-11-19(12-14-22(24)23-25)21(15-20)18-9-7-17(8-10-18)16-5-3-2-4-6-16/h2-15,25H,1H3,(H,23,24)/b14-12+
InChi Key ASHPRZYGCOMVHO-WYMLVPIESA-N
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

MDK-7933 is a potent HDAC8 inhibitor with an IC₅₀ of 27.2 nM in cancer cell lines. MDK-7933 displays antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5).


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