A caspase-1 and ACE2 substrate
Catalog #: B2717 | abID:

Product Details

Alternate Name Caspase-1 substrate, Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH., ACE2 substrate
Peptide Sequence Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH
Appearance White to yellow solid
Molecular Formula C₅₃H₆₄N₁₀O₁₉
Molecular Weight 1145.1
Purity ≥95% by HPLC
Solubility >5 mg/ml DMSO
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


MCA-YVADAP-K(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2). Upon cleavage by caspase-1 or ACE2, 7-methoxycoumarin-4-acetyl (MCA) is released and its fluorescence can be used to estimate enzyme activity. MCA displays excitation/emission maxima of 328/420 nm, respectively.

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