Product Details
| Alternate Name | salinosporamide A; (1R,4R,5S)-4-(2-chloroethyl)-1-[(S)-[(1S)-cyclohex-2-en-1-yl]-hydroxymethyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione; NPI-0052 |
|---|---|
| Appearance | Crystalline solid |
| CAS # | 437742-34-2 |
| Molecular Formula | C₁₅H₂₀ClNO₄ |
| Molecular Weight | 313.77 |
| Purity | ≥98% |
| Solubility | in DMSO |
| SMILES | CC12C(C(=O)NC1(C(=O)O2)C(C3CCCC=C3)O)CCCl |
| InChi | InChI=1S/C15H20ClNO4/c1-14-10(7-8-16)12(19)17-15(14,13(20)21-14)11(18)9-5-3-2-4-6-9/h3,5,9-11,18H,2,4,6-8H2,1H3,(H,17,19)/t9-,10+,11+,14+,15+/m1/s1 |
| InChi Key | NGWSFRIPKNWYAO-SHTIJGAHSA-N |
| PubChem CID | 11347535 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Marizomib (Salinosporamide A) is a potent, reversible, broad-spectrum, brain-penetrant proteasome inhibitor, that displays antitumor activity in vitro and in vivo.
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