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Magnetic Beads for DNA Purification

Magnetic beads to purify DNA
Catalog #: M1502
$225.00

Product Details

Cat # +Size M1502-5
Size 5 ml
Highlights • High recovery
• No salt carryover
• Cost effective
• No centrifugation or filtration required
• Seamlessly integrates into NGS Library Prep workflows
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BioVision’s Magnetic Beads for DNA Purification are paramagnetic particles coated with carboxyl groups that can reversibly bind to DNA. The magnetic beads are formulated to specifically bind to DNA and remove unwanted excess primers, adapter dimers, salts and enzymes from a wide variety of reactions. These beads can be used for PCR purification, NGS library prep cleanup and concentrating DNA. An important feature of the magnetic beads is their flexibility due to their ability to size-select the DNA fragments simply by changing the DNA:Beads ratio. BioVision’s Magnetic Beads allow for high recovery of DNA using a quick and simple procedure.


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What is the size of the Magnetic beads?
The average particle/bead size is 1 μm.
What was the sample loaded in the gel image in the datasheet? Were the magnetic beads loaded or was the supernatant loaded on the gel in figure A, B and C?
   1. The magnetic bead-bound fractions and the DNA eluted from the beads were loaded in the gels in Figures A and B. The researcher can remove larger fragments and retain smaller fragments when the unbound fraction is retained. The unbound fraction is not shown as this is not the usual use for the beads.
  2. Figure C shows the 0.9X ratio (size selection) vs 2.1X ratio (which is a positive control for DNA extraction and will retain all fragments tested). The 2.1X ratio is equivalent to an unpurified sample. It would undergo washes, elution, etc, to mimic the processing of the sample using 0.9X ratio.