Product Details
| abID | ab285538 |
|---|---|
| Alternate Name | Macrophage Colony Stimulating Factor, CSF-1, MGI-IM, Lanimostim |
| Gene Symbol | M-CSF |
| Gene ID | 1435 |
| Accession # | P09603 |
| Source | E. coli |
| Appearance | Lyophilized protein |
| Physical Form Description | Sterile filtered and then lyophilized from 5 mM Tris, pH 8.0 + 80 mM Arginine. |
| Molecular Weight | 36.8 kDa |
| Purity by SDS-PAGE | ≥98% |
| Purity by | ≥98% |
| Endotoxin Level | <0.1 ng/μg |
| Biological Activity | The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine M-NSF-60 cells is <5.0 ng/ml, corresponding to a specific activity of ≥2 x 10⁵ units/mg. |
| Reconstitution Instructions | Reconstitute in H₂O to a concentration of 0.1-0.5 mg/ml. The solution can then be diluted into other aqueous buffers |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Macrophage Colony stimulating Factor (M-CSF) is produced by various cell types, including fibroblasts, microphages, and endothelial cells. M-CSF is involved in both the development and function of monocytes/microphages. Recombinant human M-CSF is a 36.8 kDa homodimeric protein containing two 159 amino acid polypeptide subunits.
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