M-CSF, human recombinant

A hematopoietic growth factor
Catalog #: 4237 | abID: ab285538

Product Details

abID ab285538
Alternate Name Macrophage Colony Stimulating Factor, CSF-1, MGI-IM, Lanimostim
Gene Symbol M-CSF
Gene ID 1435
Accession # P09603
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and then lyophilized from 5 mM Tris, pH 8.0 + 80 mM Arginine.
Molecular Weight 36.8 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine M-NSF-60 cells is <5.0 ng/ml, corresponding to a specific activity of ≥2 x 10⁵ units/mg.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-0.5 mg/ml. The solution can then be diluted into other aqueous buffers
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans


Macrophage Colony stimulating Factor (M-CSF) is produced by various cell types, including fibroblasts, microphages, and endothelial cells. M-CSF is involved in both the development and function of monocytes/microphages. Recombinant human M-CSF is a 36.8 kDa homodimeric protein containing two 159 amino acid polypeptide subunits.

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