Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Lysosomal Cytotoxicity Dual Staining Kit (Cell-Based)

Catalog #: K458

Product Details

Cat # +Size K458-50
Size 50 assays
Kit Summary • Detection method- Flow cytometry and Fluorescence Microscopy
• Species reactivity- Mammalian
• Applications - Measurement of Lysosomal cytotoxicity
- Screening compounds affecting lysosomal function
Detection Method Flow Cytometry (FL1/FL2)
Species Reactivity Mammalian
Applications • Measurement of lysosomal cytotoxicity.
• Staining for lysosome cytotoxicity and cell death.
• Screening for compounds that affect lysosomal function
Features & Benefits Measurement of lysosomal cytotoxicity.
Kit Components • Assay Buffer (10X)
• Lysosomal Stain (500X)
• Cell Death Marker (500X)
• Positive Control Reagent
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Lysosomes are membrane-bound organelles important for various cellular processes. They contain hydrolytic enzymes utilized in the metabolism of some biomolecules. The extracellular cargo (e.g. nutrients, toxins) binds to the cell membrane and is subsequently transported into membrane-bound endosomes for further degradation by lysosomes while intracellular components are transported to lysosomes through autophagy. Lysosomal dysfunction is associated with many human conditions such as aging and neurodegenerative disease. BioVision has developed the Lysosomal Cytotoxicity Dual Staining Kit (cell-based) which contains two probes; membrane permeable, selective Lysosomal Stain and Cell Death Marker. We also include a Positive Control Reagent, which increases lysosome activity and staining, thus serves as an experimental control. This easy-to-use, non-radioactive kit allows studying the regulation of lysosome and cytotoxicity at the cellular level by using Fluorescence Microscopy and Flow Cytometry in cultured cells.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.