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Lysine-specific Demethylase Inhibitor (1C) (Hydrochloride)

An inhibitor of Lysine Specific Demethylase Inhibitor 1
Catalog #: B2814
SKU-Size Size Price Qty
B2814-1 1 mg
$65.00
B2814-5 5 mg
$245.00
More Sizes Get Quote

Product Details

Alternate Name KDM1 Inhibitor I, LSD Inhibitor I, 1,11-bis{N2,N3-dimethyl-N1-guanidino}4,8-diazaundecane, tetrahydrochloride
Appearance Crystalline solid
CAS # 1234494-75-7
Molecular Formula C₁₅H₄₀Cl₄N₈
Molecular Weight 474.34
Purity ≥95%
Solubility 50 mg/ml in Water
Soluble in DMSO
SMILES CN/C(NCCCNCCCNCCCN/C(NC)=N/C)=N\C.[H]Cl.[H]Cl.[H]Cl.[H]Cl
InChi InChI=1S/C15H36N8.4ClH/c1-16-14(17-2)22-12-6-10-20-8-5-9-21-11-7-13-23-15(18-3)19-4;;;;/h20-21H,5-13H2,1-4H3,(H2,16,17,22)(H2,18,19,23);4*1H
InChi Key ZCHKXZIIULPIMO-UHFFFAOYSA-N
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Lysine-specific Demethylase Inhibitor (1C) inhibits Lysine-specific demethylase 1 (LSD1). LSD1 removes methyl groups from histones. The inhibitor LSD 1C increased H3K4me1 and H3K4me2, without affecting H3K9me2 levels. It induced the re-expression of aberrantly silenced genes important in the development of colon cancer, including SFRPs and GATA5.


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