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Lys01 trihydrochloride

A potent, water-soluble lysosomal autophagy inhibitor
Catalog #: B2117
SKU-Size Size Price Qty
B2117-5 5 mg
$125.00
B2117-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name N2-(7-Chloro-4-quinolinyl)-N1-[2-[(7-chloro-4-quinolinyl)amino]ethyl]-N1-methyl-1,2-ethanediamine trihydrochloride; Lys05
Appearance Brown solid
CAS # 1391426-24-6
Molecular Formula C₂₃H₂₆Cl₅N₅
Molecular Weight 549.75
Purity ≥98% by HPLC
Solubility DMSO
SMILES CN(CCNC1=C2C=CC(=CC2=NC=C1)Cl)CCNC3=C4C=CC(=CC4=NC=C3)Cl.Cl.Cl.Cl
InChi InChI=1S/C23H23Cl2N5.3ClH/c1-30(12-10-28-20-6-8-26-22-14-16(24)2-4-18(20)22)13-11-29-21-7-9-27-23-15-17(25)3-5-19(21)23;;;/h2-9,14-15H,10-13H2,1H3,(H,26,28)(H,27,29);3*1H
InChi Key JTUYDBHQGOZPQQ-UHFFFAOYSA-N
PubChem CID 70673566
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Lys01 trihydrochloride (Lys05) is a potent, water-soluble lysosomal autophagy inhibitor with IC₅₀ values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay.


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