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Product Details
| Alternate Name | Ruboxistaurin |
|---|---|
| Appearance | Red solid |
| CAS # | 169939-93-9 |
| Molecular Formula | C₂₈H₂₉ClN₄O₃ |
| Molecular Weight | 505.01 |
| Purity | ≥98% by NMR |
| Solubility | DMSO |
| SMILES | CN(C)CC1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl |
| InChi | InChI=1S/C28H28N4O3.ClH/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24;/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34);1H/t18-;/m0./s1 |
| InChi Key | NYQIEYDJYFVLPO-FERBBOLQSA-N |
| PubChem CID | 9870785 |
| MDL Number | MFCD08702685 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
An isozyme-selective inhibitor of protein kinase Cβ (PKCβ). Inhibits both the PKCβI (IC₅₀ = 4.7 nM) and PKCβII (IC₅₀ = 5.9 nM) isozymes. LY-333,531 is 76- and 61-fold more selective for inhibition of PKCβI and PKCβII over PKCα.
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