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LY-333,531 hydrochloride

A protein kinase Cβ inhibitor
Catalog #: 2156
SKU-Size Size Price Qty
2156-250 250 µg
$70.00
2156-1000 1 mg
$185.00
More Sizes Get Quote

Product Details

Alternate Name Ruboxistaurin
Appearance Red solid
CAS # 169939-93-9
Molecular Formula C₂₈H₂₉ClN₄O₃
Molecular Weight 505.01
Purity ≥98% by NMR
Solubility DMSO
SMILES CN(C)CC1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl
InChi InChI=1S/C28H28N4O3.ClH/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24;/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34);1H/t18-;/m0./s1
InChi Key NYQIEYDJYFVLPO-FERBBOLQSA-N
PubChem CID 9870785
MDL Number MFCD08702685
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

An isozyme-selective inhibitor of protein kinase Cβ (PKCβ). Inhibits both the PKCβI (IC₅₀ = 4.7 nM) and PKCβII (IC₅₀ = 5.9 nM) isozymes. LY-333,531 is 76- and 61-fold more selective for inhibition of PKCβI and PKCβII over PKCα.


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