Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


A potent, selective and ATP-dependent inhibitor of checkpoint kinase 1 (Chk1)
Catalog #: B2191
SKU-Size Size Price Qty
B2191-5 5 mg
B2191-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name (S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea; Rabusertib
Appearance White to off-white solid
CAS # 911222-45-2
Molecular Formula C₁₈H₂₂BrN₅O₃
Molecular Weight 436.3
Purity ≥98% by HPLC
Solubility DMSO (~10 mg/ml)
InChi InChI=1S/C18H22BrN5O3/c1-11-5-16(27-10-13-8-20-3-4-26-13)15(6-14(11)19)23-18(25)24-17-9-21-12(2)7-22-17/h5-7,9,13,20H,3-4,8,10H2,1-2H3,(H2,22,23,24,25)/t13-/m0/s1
PubChem CID 11955855
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


LY-2603618 is a potent, selective and ATP-dependent inhibitor of checkpoint kinase 1 (Chk1) (IC₅₀ = 7 nM). It inhibits Chk1 autophosphorylation and increase DNA damage-mediated Chk1 phosphorylation. Displays antitumor activities.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.