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A potent protein kinase C (PKC) inhibitor
Catalog #: B2092
SKU-Size Size Price Qty
B2092-5 5 mg
B2092-25 25 mg
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Product Details

Alternate Name 3-amino-N-(3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl)-6-(3-(trifluoromethyl)pyridin-2-yl)pyrazine-2-carboxamide; NVP-LXS196
Appearance Crystalline solid
CAS # 1874276-76-2
Molecular Formula C₂₂H₂₃F₃N₈O
Molecular Weight 472.5
Purity ≥98% by HPLC
Solubility DMSO
InChi InChI=1S/C22H23F3N8O/c1-21(27)6-10-33(11-7-21)15-5-3-9-29-19(15)32-20(34)17-18(26)30-12-14(31-17)16-13(22(23,24)25)4-2-8-28-16/h2-5,8-9,12H,6-7,10-11,27H2,1H3,(H2,26,30)(H,29,32,34)
PubChem CID 118873253
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


LXS-196 is an orally available protein kinase C (PKC) inhibitor with potential immunosuppressive and antineoplastic activities. Upon oral administration, LXS-196 binds to and inhibits PKC, which prevents the activation of PKC-mediated signaling pathways. This may lead to the induction of cell cycle arrest and apoptosis in susceptible tumor cells.

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