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Lungkine (CXCL15), Murine Recombinant

Catalog #: P1296

In stock

SKU-Size Size Price Qty
P1296-5 5 µg
$115.00
P1296-20 20 µg
$295.00
More Sizes Get Quote

Product Details

Alternate Name CXCL15, Lungkine, Small-inducible cytokine B15, Scyb15, Weche, C-X-C motif chemokine 15
Gene Symbol Cxcl15
Accession # Q3UQ15
Source E. Coli
Appearance Lyophilized
Physical Form Description Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4, with 0.02 % Tween-20.
Molecular Weight 16.3 kDa
Purity by SDS-PAGE ≥ 98%
Endotoxin Level <0.1 EU/μg
Biological Activity Determined by its ability to chemoattract human neutrophils using a concentration range of 20.0-100.0 ng/ml.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended reconstitute with sterilized distilled water or 0.1% BSA aqueous buffer and store in working aliquots at -20°C to -80°C.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Lungkine is a CXC chemokine that is expressed in lung epithelial cells and, to a lesser extent, in certain fetal tissues. No human homolog has been identified and a specific cell surface receptor has not yet been found. Lungkine expression in lung tissue is elevated in response to inflammation, at which time it acts to specifically recruit neutrophils and direct them into the lung airway. Recombinant murine Lungkine is a 16.3 kDa CXC chemokine consisting of 142 amino acid residues, including four conserved cysteine residues present in CXC chemokines.


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