Product Details
| abID | ab287083 |
|---|---|
| Alternate Name | 8-(4-Dibenzothienyll)-2-(4-morpholinyl)-4H-1,3-benzoxazin-4-one; LTURM34 |
| Peptide Sequence | N/A |
| Appearance | Off-white solid |
| CAS # | 1879887-96-3 |
| Molecular Formula | C₂₄H₁₈N₂O₃S |
| Molecular Weight | 414.48 |
| Purity | ≥98% by HPLC |
| Solubility | >20 mg/ml in DMSO |
| SMILES | C1COCCN1C2=NC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56 |
| InChi | InChI=1S/C24H18N2O3S/c27-23-19-9-3-6-16(21(19)29-24(25-23)26-11-13-28-14-12-26)18-8-4-7-17-15-5-1-2-10-20(15)30-22(17)18/h1-10H,11-14H2 |
| InChi Key | SMMSWOMXOZLOPI-UHFFFAOYSA-N |
| PubChem CID | 122705987 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
LTURM-34 is a potent DNA-PK inhibitor (IC₅₀ = 34 nM). Displays 170-fold selectivity for DNA-PK over PI3-K. Attenuates proliferation of a wide range of tumor cell lines in vitro.
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