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Loxoribine

A selective TLR7 ligand
Catalog #: 2003
SKU-Size Size Price Qty
2003-5 5 mg
$80.00
2003-25 25 mg
$265.00
More Sizes Get Quote

Product Details

Alternate Name 7-Allyl-8-oxoguanosine ; RWJ21757
Appearance White solid
CAS # 121288-39-9
Molecular Formula C₁₃H₁₇N₅O₆
Molecular Weight 339.3
Purity ≥97% by HPLC
Solubility DMSO (30 mg/ml) or water (10 mg/ml)
SMILES C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O
InChi InChI=1S/C13H17N5O6/c1-2-3-17-6-9(15-12(14)16-10(6)22)18(13(17)23)11-8(21)7(20)5(4-19)24-11/h2,5,7-8,11,19-21H,1,3-4H2,(H3,14,15,16,22)/t5-,7-,8-,11-/m1/s1
InChi Key VDCRFBBZFHHYGT-IOSLPCCCSA-N
PubChem CID 60737
MDL Number MFCD00867591
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A guanosine derivative that acts as a selective ligand for Toll-like receptor 7 (TLR7) via IFN. Activates natural killer cells and primes cytolytic precursor cells for activation by IL-2.


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