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A selective farnesyltransferase inhibitor
Catalog #: B1616

In stock

SKU-Size Size Price Qty
B1616-5 5 mg
B1616-25 25 mg

Product Details

Alternate Name Sarasar; SCH 66336; SCH66336; SCH-66336, 4-(2-(4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxamide; farnesyltransferase inhibitor; FTI inhibitor
Appearance Solid
CAS # 193275-84-2 
Molecular Formula C₂₇H₃₁Br₂ClN₄O₂
Molecular Weight 638.82
Purity ≥98%
Solubility DMSO (127 mg/mL, 198.8 mM)
InChi 1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11H2,(H2,31,36)/t25-/m1/s1
PubChem CID 148195
MDL Number MFCD06795138
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Lonafarnib (SCH 66336) is a selectively farnesyltransferase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.

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