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Lomeguatrib

A potent MGMT inhibitor
Catalog #: 2224
SKU-Size Size Price Qty
2224-5 5 mg
$65.00
2224-25 25 mg
$255.00
More Sizes Get Quote

Product Details

Alternate Name PaTrin-2; 6-​[(4-​bromo-​2-​thienyl)methoxy]-​9H-​purin-​2-​amine
Appearance Off-white solid
CAS # 192441-08-0
Molecular Formula C₁₀H₈BrN₅OS
Molecular Weight 326.17
Purity ≥98% by HPLC
Solubility DMSO (100 mM)
SMILES C1=C(SC=C1Br)COC2=NC(=NC3=C2NC=N3)N
InChi InChI=1S/C10H8BrN5OS/c11-5-1-6(18-3-5)2-17-9-7-8(14-4-13-7)15-10(12)16-9/h1,3-4H,2H2,(H3,12,13,14,15,16)
InChi Key JUJPKFNFCWJBCX-UHFFFAOYSA-N
PubChem CID 3025944
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Lomeguatrib is a potent inhibitor of DNA repair protein O6-Methylguanine-DNA methyltransferase (MGMT) and related mammalian proteins. PaTrin-2 displays nanomolar activity in vitro and in vivo.


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