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LLL12

A Stat3 phosphorylation inhibitor
Catalog #: 1792
SKU-Size Size Price Qty
1792-5 5 mg
$140.00
1792-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name 5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide
Appearance Lyophilized solid
Molecular Formula C₁₄H₉NO₅S
Molecular Weight 303.29
Purity ≥95% by ¹H NMR
Solubility DMSO
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast and pancreatic cancer cells as well as in glioblastoma cells. LLL12 has minimal apoptotic effects on normal human cells.


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