Product Details
| Alternate Name | 5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide |
|---|---|
| Appearance | Lyophilized solid |
| CAS # | 1260247-42-4 |
| Molecular Formula | C₁₄H₉NO₅S |
| Molecular Weight | 303.29 |
| Purity | ≥95% by ¹H NMR |
| Solubility | DMSO |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast and pancreatic cancer cells as well as in glioblastoma cells. LLL12 has minimal apoptotic effects on normal human cells.
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