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New

LIX (CXCL6), Murine Recombinant

Chemoattractant for neutrophils
Catalog #: P1293

In stock

SKU-Size Size Price Qty
P1293-5 5 µg
$115.00
P1293-20 20 µg
$295.00
More Sizes Get Quote

Product Details

Alternate Name CXCL6, GCP-2 (human), Granulocyte Chemotactic Protein-2
Source E. Coli
Appearance Lyophilized
Molecular Weight 9.8 kDa
Purity by SDS-PAGE ≥ 98%
Endotoxin Level <0.1 EU/μg
Biological Activity Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to aliquot and store at -20°C to -80°C.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant murine LIX is a 9.8 kDa protein containing 92 amino acid residues.


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