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Lisinopril dihydrate

A potent angiotensin converting-Enzyme (ACE) inhibitor
Catalog #: B2132

In stock

SKU-Size Size Price Qty
B2132-50 50 mg
$75.00
B2132-250 250 mg
$225.00
More Sizes Get Quote

Product Details

Alternate Name (S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, Lisinopril, MK-521
Appearance White solid
CAS # 83915-83-7
Molecular Formula C₂₁H₃₁O₅N₃ · 2H₂O
Molecular Weight 441.52
Purity ≥98% by HPLC
Solubility H₂O (~10 mg/ml) or DMSO (~ 5 mg/ml)
SMILES C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O.O.O
InChi InChI=1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1
InChi Key CZRQXSDBMCMPNJ-ZUIPZQNBSA-N
PubChem CID 5362118
MDL Number MFCD01698825
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Lisinopril is a potent angiotensin converting-Enzyme (ACE) inhibitor (IC₅₀ = 4.7 nM). The administration of lisinopril can lower the diastolic and systolic blood pressure and higher the heart rate. Lisinopril is found to reduce the activity of plasma angiotensin converting enzyme markedly. It increases the level of plasma rennin while decreases the levels of plasma Angiotensin II and aldosterone.


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