Liproxstatin-1 (ab287002)
Key features and details
- Potent inhibitor of ferroptosis.
- CAS Number: 950455-15-9
- Purity: >= 98%
Soluble in DMSO to 25mM
- Form / State: Solid
Overview
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Product name
Liproxstatin-1 -
Description
Potent inhibitor of ferroptosis. -
Alternative names
- N-[(3-chlorophenyl)methyl]spiro[4H-quinoxaline-3,4'-piperidine]-2-amine
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Biological description
A potent inhibitor of ferroptosis. Liproxstatin-1 suppresses ferroptosis in human cells and in an ischemia/reperfusion-induced tissue injury model in mice.
Knockout of glutathione peroxidase 4 (Gpx4) Has been shown to cause cell death by ferroptosis. Liproxstatin-1 was able to suppress ferroptosis in Gpx4 knock-out mice. -
Purity
>= 98% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called B2312 Liproxstatin-1. B2312-5 is the same size as the 5 mg size of ab287002.
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CAS Number
950455-15-9
Properties
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Chemical name
N-[(3-chlorophenyl)methyl]-spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine
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Molecular weight
340.85 -
Molecular formula
C19H21ClN4 -
PubChem identifier
135735917 -
Storage instructions
Shipped at 4°C. Store at -20°C. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Soluble in DMSO to 25mM
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SMILES
C1CNCCC12C(=NC3=CC=CC=C3N2)NCC4=CC(=CC=C4)Cl
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab287002 has not yet been referenced specifically in any publications.