Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


LIN28 inhibitor LI71

An inhibitor of LIN28
Catalog #: B3073
SKU-Size Size Price Qty
B3073-5 5 mg
B3073-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 4-[(3aS,4R,9bR)-6-ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acid
Appearance White powder
CAS # 1357248-83-9
Molecular Formula C₂₁H₂₁NO₃
Molecular Weight 335.4
Purity ≥97%
Solubility Soluble in methanol
InChi InChI=1S/C21H21NO3/c1-2-25-18-8-4-7-17-15-5-3-6-16(15)19(22-20(17)18)13-9-11-14(12-10-13)21(23)24/h3-5,7-12,15-16,19,22H,2,6H2,1H3,(H,23,24)/t15-,16+,19+/m1/s1
PubChem CID 6541811
MDL Number MFCD07363437
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


LIN28 is an RNA-binding protein that regulates the maturation of the let-7 microRNAs through its two distinct cold shock and zinc-knuckle domains. LIN28 inhibitor LI71 binds the cold shock domain of LIN28 and suppresses the activity of LIN28 against let-7 in leukemia cells and embryonic stem cells. LI71 shows an IC₅₀ of ~7 μM in the fluorescence polarization assay using LIN28 and pre-elements of members of the let-7 family.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.