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LIGHT, Murine Recombinant

Apoptosis inducer
Catalog #: P1292

In stock

SKU-Size Size Price Qty
P1292-5 5 µg
$115.00
P1292-20 20 µg
$295.00
More Sizes Get Quote

Product Details

Alternate Name TNFSF14, HVEM-L, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, Herpesvirus entry mediator ligand, CD258, LIGHT
Accession # Q9QYH9
Source E. Coli
Appearance Lyophilized
Physical Form Description Lyophilized from 20mM Tris, pH 8.5 + 100 mM Arginine.
Molecular Weight 20.1 kDa
Purity by SDS-PAGE ≥ 98%
Endotoxin Level <0.1 EU/μg
Reconstitution Instructions DI water (~1 mg/ml)
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFκB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.


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