Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


An orally available inhibitor of microtubule polymerization
Catalog #: B3096
SKU-Size Size Price Qty
B3096-1 1 mg
B3096-5 5 mg
More Sizes Get Quote

Product Details

Alternate Name CYT997; 1-ethyl-3-[2-methoxy-4-[5-methyl-4-[[(1S)-1-pyridin-3-ylbutyl]amino]pyrimidin-2-yl]phenyl]urea
Appearance White to off-white solid
CAS # 917111-44-5
Molecular Formula C₂₄H₃₀N₆O₂
Molecular Weight 434.5
Purity ≥ 97%
Solubility ~20 mg/ml in DMSO or DMF, ~16 mg/ml in ethanol
InChi InChI=1S/C24H30N6O2/c1-5-8-19(18-9-7-12-25-15-18)28-22-16(3)14-27-23(30-22)17-10-11-20(21(13-17)32-4)29-24(31)26-6-2/h7,9-15,19H,5-6,8H2,1-4H3,(H2,26,29,31)(H,27,28,30)/t19-/m0/s1
PubChem CID 11351021
MDL Number MFCD18206787
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


Lexibulin is an orally available inhibitor of microtubule polymerization with an IC₅₀ of 3 µM. It blocks cell cycle at the G2-M phase, which leads to cell death. It is cytotoxic to various cell lines with IC₅₀ values ranging from 10-100 nM. It shows antitumor activity in prostate cancer and breast cancer in vivo models. It exhibits antivascular activity in vitro and in vivo.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.