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Letrozole

A nonsteroidal aromatase inhibitor
Catalog #: B2042

In stock

SKU-Size Size Price Qty
B2042-50 50 mg
$85.00
B2042-250 250 mg
$325.00
More Sizes Get Quote

Product Details

Alternate Name 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
Appearance White to off-white solid
CAS # 112809-51-5
Molecular Formula C₁₇H₁₁N₅
Molecular Weight 285.3
Purity ≥98% by HPLC
Solubility DMSO (>50 mg/ml)
SMILES C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3
InChi InChI=1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
InChi Key HPJKCIUCZWXJDR-UHFFFAOYSA-N
PubChem CID MFCD00866241
MDL Number 3902
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Letrozole is a third-generation nonsteroidal cell-permeable aromatase inhibitor (IC₅₀ = 2 nM). It is a competitive inhibitor of the aromatase enzyme system and thus inhibits the conversion of androgens to estrogens. Useful in the treatment of postmenopausal breast cancer.


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