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Lesinurad Sodium

A seletive URAT1 inhibitor
Catalog #: B3330
SKU-Size Size Price Qty
B3330-10 10 mg
$95.00
B3330-50 50 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name N-[(2S)-1-[[(E,3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpiperazine-1-carboxamide
Appearance Solid
CAS # 1151516-14-1
Molecular Formula C₁₇H₁₃BrN₃NaO₂S
Molecular Weight 426.26
Purity ≥98%
Solubility >25 mg/ml DMSO
SMILES C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)[O-].[Na+]
InChi InChI=1S/C17H14BrN3O2S.Na/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14;/h1-4,7-8,10H,5-6,9H2,(H,22,23);/q;+1/p-1
InChi Key FVYMVLTWIBGEMC-UHFFFAOYSA-M
PubChem CID 56928182
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Lesinurad (RDEA-594) sodium is a selective uric acid reabsorption inhibitor (SURI). Lesinurad sodium also inhibits the uric acid transporter URAT1 and Kidney transporter OAT with IC50/Km of 4.3 μM/0.85 μM and 3.5 μM/2 μM for OAT1 and OAT3, respectively.


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