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Leptin, murine recombinant

Adipose-derived hormone which regulates energy intake & energy expenditure
Catalog #: 4367

In stock

SKU-Size Size Price Qty
4367-02 200 μg
$85.00
4367-1 1 mg
$200.00
4367-5 5 mg
$490.00
More Sizes Get Quote

Product Details

Alternate Name OB Protein, Obesity Protein, OBS, Obesity factor.
Gene Symbol LEP
Gene ID 16846
Accession # P41160
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized with no additives
Molecular Weight 16.2 kDa
Purity by SDS-PAGE ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity Determined in an in vivo assay using the ob/ob mouse obesity model and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 µg leptin/gm of body weight for 7 days. Significant effects on body weight, food consump
Reconstitution Instructions Reconstitute in 10 mM HCl to a concentration of 1 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the body’s fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Murine Leptin is a 16 kDa protein containing 147 amino acid residues.


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