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Leptin, human recombinant

Adipose-derived hormone which regulates energy intake & energy expenditure
Catalog #: 4366
SKU-Size Size Price Qty
4366-02 200 μg
$80.00
4366-1 1 mg
$190.00
4366-5 5 mg
$490.00
4366-10 10 mg
$695.00
More Sizes Get Quote

Product Details

Alternate Name OB Protein, Obesity Protein, OBS, Obesity factor.
Gene Symbol LEP
Gene ID 3952
Accession # P41159
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized
Molecular Weight 16.0 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity BioVision’s human Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 mg Leptin/gm of body weight for 7 days. Signi
Reconstitution Instructions Add 15 mM sterile HCl (0.5 ml/1 mg vial or 5 ml/10 mg vial) to the vial. After the protein is completely dissolved, add 7.5 mM sterile NaOH (0.3 ml/1 mg vial or 3 ml/10 mg vial) to bring the pH to approximately 5.2.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the body’s fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Human Leptin is a 16 kDa protein containing 146 amino acid residues.


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