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Product Details
| Alternate Name | OB Protein, Obesity Protein, OBS, Obesity factor. |
|---|---|
| Gene Symbol | LEP |
| Gene ID | 280836 |
| Accession # | P50595 |
| Source | E. coli |
| Appearance | Lyophilized |
| Physical Form Description | Lyophilized from a concentrated (1mg/ml) solution with 0.0045 mM NaHCO3. |
| Molecular Weight | 16 kDa. |
| Purity by SDS-PAGE | 95% |
| Biological Activity | Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. |
| Reconstitution Instructions | It is recommended to reconstitute the lyophilized Leptin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Amino Acid Sequence | Protein has146 amino acids. The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Pro-Ile-Arg. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A 16-kDa peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Leptin provides the key afferent signal from fat cells in the feedback system that controls body fat stores
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