Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

LDN-192960 hydrochloride

A Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) inhibitor
Catalog #: B3285
SKU-Size Size Price Qty
B3285-5 5 mg
$125.00
B3285-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name 3-[(2,7-dimethoxy-9-acridinyl)thio]-1-propanamine, dihydrochloride
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 2309172-48-1
Molecular Formula C₁₈H₂₀N₂O₂S • 2HCl
Molecular Weight 401.4
Purity ≥98%
Solubility >30 mg/ml DMSO
SMILES COC1=CC2=C(SCCCN)C3=CC(OC)=CC=C3N=C2C=C1.Cl.Cl
InChi InChI=1S/C18H20N2O2S.2ClH/c1-21-12-4-6-16-14(10-12)18(23-9-3-8-19)15-11-13(22-2)5-7-17(15)20-16;;/h4-7,10-11H,3,8-9,19H2,1-2H3;2*1H
InChi Key FNHCUCJBABESJB-UHFFFAOYSA-N
PubChem CID 91885401
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

LDN-192960 dihydrochloride is an inhibitor of Haspin protein kinase and dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) with IC50 values of 10 and 48 nM, respectively. It displays selectivity for Haspin and DYRK2 over TRKB, CLK1, DYRK1A, DYRK3, ROS, HIPK1, HIPK2, PIM-1, and PIM-2 kinases (IC50s = 720-91,000 nM).


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.