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LAG-1 (CCL4L1), Human Recombinant

LAG-1 is CC chemokine that signals through the CCR5 receptor
Catalog #: P1290

In stock

SKU-Size Size Price Qty
P1290-5 5 µg
$115.00
P1290-20 20 µg
$295.00
More Sizes Get Quote

Product Details

Alternate Name Lymphocyte Activation Gene-1, CCL4L1, ACT-2, T-cell activiation-2, HC21, C-C motif chemokine 4-like, Lymphocyte activation gene 1 protein, LAG-1, Macrophage inflammatory protein 1-beta, MIP-1-beta, Monocyte adherence-induced protein 5-alpha, Small-inducible cytokine A4-like
Accession # Q8NHW4
Source E.coli
Appearance Lyophilized
Physical Form Description Lyophilized with no additives.
Molecular Weight 7.7 kDa
Purity by SDS-PAGE ≥ 98%
Endotoxin Level <0.1 EU/μg
Biological Activity Determined by its ability to chemoattract CCR5 transfected cells using a concentration of 0.1-10.0 ng/ml
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

LAG-1 is CC chemokine receptor (beta chemokine receptors) that signals through the CCR5 receptor. LAG-1 is identical to MIP-1β (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.


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