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L3MBTL1 polyclonal antibody

Polyclonal Antibody to detect L3MBTL1 in human samples.
Catalog #: 6857
$275.00

Product Details

Cat # +Size 6857-25
Size 25 μg
Antibody Target L3MBTL1
Alternate Name L3MBTL, L3MBT
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Polyclonal antibody raised in rabbit against human L3MBTL1 (lethal 3 malignant brain tumor-like protein), using the N-terminal part of the protein.
Accession # Q9Y468
Gene ID 26013
Appearance Colorless liquid
Formulation In PBS with 0.05% sodium azide and 0.05% ProClin 300.
Purification Protein G purified
Species Reactivity Human.
Application Western blot, IP.
Positive Control Western blot: HeLa cells, IP: HeLa cells
Application & Usage Western Blot: 1:1000, IP: 1 - 5 µg/IP
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

L3MBTL1 is a member of the polycomb group (PcG) proteins, which function as transcriptional regulators in large protein complexes. In Drosophila, homozygous mutations in the L3MBTL1 gene have been demonstrated to cause brain tumors, identifying L3MBTL1 as a tumor suppressor gene. L3MBTL1 forms a homodimer and interacts with TEL (ETV6). L3MBTL1 probably plays a role in cell proliferation. Overexpression of L3MBTL1 induces multinucleated cells, suggesting that it is required for normal mitosis.


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