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L-JNK Peptide Inhibitor I

A cell-permeable JNK inhibitor
Catalog #: 7011
$135.00

Product Details

Cat # +Size 7011-50
Size 50 µl
Peptide Sequence GRKKRRQRRR-PP-RPKRPTTLNLFPQVPRSQD-amide
Appearance Liquid
Formulation 1 mM (PBS)
Molecular Formula C₁₆₄H₂₈₆N₆₆O₄₀
Molecular Weight 3822.5
Purity ≥97% by HPLC
MDL Number MFCD12912420
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

L-JNK Peptide Inhibitor competitively blocks the interaction between JNK and c-Jun, thereby inhibiting the signaling events downstream of JNK, like c-Jun, ATF-2 and ELK1 phosphorylation. To convert JIP-1/IB-1 into cell permeable inhibitors of JNK (JNKI1) the minimal 20 amino acids inhibitory sequence of JIP-1/IB1 was covalently linked to the 10 amino acids recognized by TAT transporter. The L-JNKI1 is a potent inhibitor that is specific for JNK and can be used for in vitro applications.


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