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L-DON

A glutamine antagonist
Catalog #: B1955

In stock

SKU-Size Size Price Qty
B1955-5 5 mg
$85.00
B1955-25 25 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name H-Glu(diazomethylketone)-OH, 6-Diazo-5-oxo-L-2-aminohexanoic acid; 6-Diazo-5-oxo-L-norleucine
Appearance Yellow solid
CAS # 157-03-9
Molecular Formula C₆H₉N₃O₃
Molecular Weight 171.16
Purity ≥95% by TLC
Solubility PBS (pH 7.2, 10 mg/ml)
SMILES C(CC(=C[N+]#N)[O-])C(C(=O)O)N
InChi InChI=1S/C6H9N3O3/c7-5(6(11)12)2-1-4(10)3-9-8/h3,5H,1-2,7H2,(H-,10,11,12)/b4-3-/t5-/m0/s1
InChi Key MKZFABOMIIHLIT-XUELKZDXSA-N
PubChem CID 5359375
MDL Number MFCD00037218
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

L-DON is a glutamine antagonist produced naturally by Streptomyces; it inhibits several glutamine-dependent enzyme pathways as well as acts as an inhibitor of the mitochondrial enzyme, glutaminase (GLS), the primary producer of neuronal glutamate.


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