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L-778123 hydrochloride

A potent FPTase and GGPTase-I inhibitor
Catalog #: 9638
SKU-Size Size Price Qty
9638-10 10 mg
$145.00
9638-50 50 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name 4-((5-((4-(3-chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile hydrochloride
Appearance Crystalline solid
CAS # 253863-00-2
Molecular Formula C₂₂H₂₀ClN₅O
Molecular Weight 405.88
Purity ≥98% by HPLC
Solubility DMSO
SMILES C1CN(C(=O)CN1CC2=CN=CN2CC3=CC=C(C=C3)C#N)C4=CC(=CC=C4)Cl.Cl
InChi InChI=1S/C22H20ClN5O.ClH/c23-19-2-1-3-20(10-19)28-9-8-26(15-22(28)29)14-21-12-25-16-27(21)13-18-6-4-17(11-24)5-7-18;/h1-7,10,12,16H,8-9,13-15H2;1H
InChi Key YNBSQYGTJLIPJS-UHFFFAOYSA-N
PubChem CID 216453
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

L-778123 hydrochloride is a potent inhibitor of FPTase and GGPTase-I with an IC₅₀ of 2 nM and 98 nM, respectively, in enzyme inhibition determination.


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