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A protein kinase G (PKG) inhibitor
Catalog #: 2164
SKU-Size Size Price Qty
2164-50 50 µg
2164-250 250 µg
More Sizes Get Quote

Product Details

Alternate Name 2,​3,​9,​10,​11,​12-​hexahydro-​10R-​methoxy-​2,​9-​dimethyl-​1-​oxo-​ 9S,​12R-​epoxy-​1H-​diindolo[1,​2,​3-​fg:3’,​2’,​1’-​kl]pyrrolo[3,​4-​ i][1,​]benzodiazocine-​10-​carboxylic acid,​ methyl ester
Appearance White solid
CAS # 126643-37-6
Molecular Formula C₂₉H₂₅N₃O₅
Molecular Weight 495.53
Purity ≥98% by HPLC
Solubility DMSO (20 mg/ml)
InChi InChI=1S/C29H25N3O5/c1-28-29(36-4,27(34)35-3)13-20(37-28)31-18-11-7-5-9-15(18)22-23-17(14-30(2)26(23)33)21-16-10-6-8-12-19(16)32(28)25(21)24(22)31/h5-12,20H,13-14H2,1-4H3
PubChem CID 3843
MDL Number MFCD09878278
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. KT5823 is a derivative of K-252a (Cat. No. 2013) that acts as a selective inhibitor of Protein kinase G (PKG) (Ki = 0.234 µM). Inhibits other kinases at much higher concentrations (Ki’s for PKA = 4 μM and for MLCK=>10 μM).

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