Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


A Ca²⁺/calmodulin-dependent kinase type II inhibitor
Catalog #: 2524
SKU-Size Size Price Qty
2524-250 250 µg
2524-1000 1 mg
More Sizes Get Quote

Product Details

Alternate Name N-​[2-​[[[3-​(4-​chlorophenyl)-​2-​propen-​1-​yl]methylamino]methyl]phenyl]-​N-​(2-​hydroxyethyl)-​4-​methoxy-​benzenesulfonamide
Appearance White solid
CAS # 139298-40-1
Molecular Formula C₂₆H₂₉ClN₂O₄S
Molecular Weight 501.04
Purity ≥98%
Solubility DMSO (>40 mg/ml)
InChi InChI=1S/C26H29ClN2O4S/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25/h3-16,30H,17-20H2,1-2H3/b6-5+
PubChem CID 5312122
MDL Number MFCD03788201
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. KN-93 is a potent inhibitor of Ca²⁺/calmodulin-dependent kinase type II (CaM kinase II) (IC₅₀ = 0.37 μM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. Also a direct extracellular open channel blocker of voltage-gated potassium channels (IC₅₀ = 307 nM for Kv1.5). More recently, KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.