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KN-92 phosphate

An inactive analog of the CaM kinase II inhibitor KN 93
Catalog #: B1644
SKU-Size Size Price Qty
B1644-5 5 mg
$85.00
B1644-25 25 mg
$315.00
More Sizes Get Quote

Product Details

Alternate Name KN-92 phosphate, KN92 phosphate; KN 92 phosphate; KN92; KN-92; N-[2-[[[(E)-3-(4-chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-4-methoxybenzenesulfonamide;phosphoric acid
Appearance Solid
CAS # 1135280-28-2
Molecular Formula C₂₄H₂₅ClN₂O₃S.H₃PO₄
Molecular Weight 554.98
Purity >98%
Solubility DMSO
SMILES CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2NS(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O
InChi 1S/C24H25ClN2O3S.H3O4P/c1-27(17-5-6-19-9-11-21(25)12-10-19)18-20-7-3-4-8-24(20)26-31(28,29)23-15-13-22(30-2)14-16-23;1-5(2,3)4/h3-16,26H,17-18H2,1-2H3;(H3,1,2,3,4)/b6-5+;
InChi Key XRQHWVVDNMJDEQ-IPZCTEOASA-N
PubChem CID 16219540
MDL Number MFCD24369012
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

KN-92 is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).


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