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KH7

A selective inhibitor of soluble adenylyl cyclase (sAC)
Catalog #: 2350
SKU-Size Size Price Qty
2350-5 5 mg
$125.00
2350-25 25 mg
$475.00
More Sizes Get Quote

Product Details

Alternate Name 2-​(1H-​benzimidazol-​2-​ylthio)-​2-​[(5-​bromo-​2-​hydroxyphenyl)methylene]hydrazide,​ propanoic acid
Appearance White solid
CAS # 330676-02-3
Molecular Formula C₁₇H₁₅BrN₄O₂S
Molecular Weight 419.3
Purity ≥98%
Solubility DMSO (~40 mg/ml)
SMILES CC(C(=O)NNC=C1C=C(C=CC1=O)Br)SC2=NC3=CC=CC=C3N2
InChi InChI=1S/C17H15BrN4O2S/c1-10(25-17-20-13-4-2-3-5-14(13)21-17)16(24)22-19-9-11-8-12(18)6-7-15(11)23/h2-10,19H,1H3,(H,20,21)(H,22,24)
InChi Key GEHVZUUHMWNMAY-UHFFFAOYSA-N
PubChem CID 6843191
MDL Number MFCD01230899
Handling Protect from air and light
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A selective inhibitor of soluble adenylyl cyclase (sAC) ( IC₅₀ = 3-10 µM in vivo). Displays little effect on transmembrane adenylyl cyclases. KH7 is not active against sAC in the presence of detergents. At concentrations above 50 µM, KH7 exhibits non-specific membrane disruption effects when used on cells.


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