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An antifungal agent
Catalog #: B2735
SKU-Size Size Price Qty
B2735-50 50 mg
B2735-250 250 mg
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Product Details

Alternate Name Fungoral 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
Peptide Sequence N/A
Appearance Off-white solid
CAS # 65277-42-1
Molecular Formula C₂₆H₂₈Cl₂N₄O₄
Molecular Weight 531.43
Purity ≥98%
Solubility ~ 2 mg/ml DMSO
InChi InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m0/s1
PubChem CID 456201
MDL Number MFCD00058579
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Ketoconazole is a broad-spectrum triazole antifungal agent. It inhibits the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol 14α-demethylase, which arrests ergosterol biosynthesis at the fungal membrane. Ketoconazole also inhibits human CYP3A4 (IC50 = 0.54 µM). Formulations containing ketoconazole have been used in the treatment of fungal infections.

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