Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

KDM1B polyclonal antibody

Polyclonal Antibody to detect KDM1B in human samples.
Catalog #: 6847
$185.00

Product Details

Cat # +Size 6847-50
Size 50 μl
Antibody Target KDM1B
Alternate Name AOF1, LSD2, C6orf193
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Polyclonal antibody raised in rabbit against human KDM1B (lysine (K)-specific demethylase 1B) using two KLH conjugated synthetic peptides containing a sequence from the N-terminal and the central region of the protein, respectively.
Accession # Q8NB78
Gene ID 221656
Appearance Colorless liquid
Formulation In PBS with 0.05% (W/V) sodium azide.
Purification Whole Anti-Sera
Species Reactivity Human.
Application ELISA.
Positive Control ELISA: Peptides.
Application & Usage ELISA: 1:500.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.