Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

KC7F2

A small molecule HIF-1 pathway inhibitor
Catalog #: 9641
SKU-Size Size Price Qty
9641-10 10 mg
$95.00
9641-50 50 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name N,N'-(dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonamide
Appearance White solid
CAS # 927822-86-4
Molecular Formula C₁₆H₁₆Cl₄N₂O₄S₄
Molecular Weight 570.38
Purity ≥98% by HPLC
Solubility DMSO (>50 mg/ml)
SMILES C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl
InChi InChI=1S/C16H16Cl4N2O4S4/c17-11-1-3-13(19)15(9-11)29(23,24)21-5-7-27-28-8-6-22-30(25,26)16-10-12(18)2-4-14(16)20/h1-4,9-10,21-22H,5-8H2
InChi Key REQLACDIZMLXIC-UHFFFAOYSA-N
PubChem CID 16047442
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

KC7F2 is a small molecule HIF-1 pathway inhibitor that inhibits HIF-1α protein translation, but not transcription. It inhibits hypoxia-induced expression of several HIF target genes, such as carbonic anhydrase IX, matrix metalloproteinase 2, enolase 1, and endothelin 1. KC7F2 is cytotoxic to a variety of cancer cell lines with an IC₅₀ value of 15-25 µM.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.