Kartogenin

A stem cell differentiating agent
Catalog #: 2066 | abID:

Product Details

Alternate Name 2-([1,1'-biphenyl]-4-ylcarbamoyl)benzoic acid
Appearance White solid
CAS # 4727-31-5
Molecular Formula C₂₀H₁₅NO₃
Molecular Weight 317.34
Purity ≥99% by TLC
Solubility DMSO (~ 60 mg/ml) or EtOH (~ 14 mg/ml)
SMILES C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O
InChi InChI=1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
InChi Key SLUINPGXGFUMLL-UHFFFAOYSA-N
PubChem CID 2826191
MDL Number MFCD00560510
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. Kartogenin promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes (EC₅₀ = 100 nM). Displays chondroprotective effects in vitro and is efficacious in two animal models of osteoarthritis.


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