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K-7174 dihydrochloride

A novel cell adhesion inhibitor
Catalog #: 9478
SKU-Size Size Price Qty
9478-5 5 mg
$145.00
9478-25 25 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name 1,4-bis((E)-5-(3,4,5-trimethoxyphenyl)pent-4-en-1-yl)-1,4-diazepane dihydrochloride
Appearance White to off-white solid
CAS # 191089-60-8
Molecular Formula C₃₃H₅₀BrCl₂N₂O6
Molecular Weight 641.67
Purity ≥98% by HPLC
Solubility DMSO (>6 mg/ml)
SMILES COC1=C(OC)C(OC)=CC(/C=C/CCCN2CCN(CCC/C=C/C3=CC(OC)=C(OC)C(OC)=C3)CCC2)=C1.[H]Cl.[H]Cl
InChi InChI=1S/C33H48N2O6.2ClH/c1-36-28-22-26(23-29(37-2)32(28)40-5)14-9-7-11-16-34-18-13-19-35(21-20-34)17-12-8-10-15-27-24-30(38-3)33(41-6)31(25-27)39-4;;/h9-10,14-15,22-25H,7-8,11-13,16-21H2,1-6H3;2*1H/b14-9+,15-10+;;
InChi Key JKAQFPBRMVEHBD-CHBZAFCASA-N
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α. K7174 also ameliorated anemia induced by inflammatory cytokines in mice.


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