A novel c-Met tyrosine kinase inhibitor
Catalog #: B2063 | abID:

Product Details

Alternate Name 6-(difluoro(6-(1-methyl-1H-pyrazol-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline
Appearance Crystalline solid
CAS # 943540-75-8
Molecular Formula C₁₉H₁₃F₂N₇
Molecular Weight 377.35
Purity ≥98% by HPLC
Solubility DMSO
InChi InChI=1S/C19H13F2N7/c1-27-11-13(10-23-27)16-6-7-17-24-25-18(28(17)26-16)19(20,21)14-4-5-15-12(9-14)3-2-8-22-15/h2-11H,1H3
PubChem CID 46911863
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


JNJ-38877605 is a potent c-MET tyrosine kinase inhibitor with potential anti-neoplastic activity. It is potent (IC₅₀ values of 4 nM and 50 nM for c-MET enzyme and Phospho-MET respectively). Displays selectivity over 229 other kinases tested.

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